Opportunity Information: Apply for RFA IP 23 002

The grant opportunity titled "Understanding Adult Immunization Quality Improvement Approaches Among Adult HCP and Health Departments" (Funding Opportunity Number RFA IP 23 002) is a discretionary federal funding announcement from the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), administered through the CDC electronic research administration system (ERA). It is offered as a cooperative agreement, which typically means the CDC expects to have substantial involvement with the recipient during the project period, not just a hands-off role as a funder. The overall focus sits within the CDCs Immunization Services Division and the National Center for Immunization and Respiratory Diseases (NCIRD), aligning with their broader priority of improving adult vaccination coverage and closing persistent gaps in adult immunization delivery.

At its core, the NOFO is designed to support research that identifies and evaluates quality improvement (QI) interventions aimed specifically at adult immunization providers, and to better understand how immunization programs and health departments can support those provider-focused improvements. In practical terms, this is about figuring out which QI strategies actually work in real-world adult care settings to increase vaccination uptake, improve the reliability and consistency of recommending and administering vaccines, strengthen systems that prompt vaccination, and reduce missed opportunities during routine healthcare visits. The opportunity also emphasizes learning what health departments and immunization programs can do to enable, reinforce, or scale those improvements, recognizing that provider behavior and system performance are often shaped by program supports such as data access, reminder and recall capabilities, training, technical assistance, policy levers, partnerships, and immunization information systems.

A major feature of this opportunity is its explicit emphasis on improving adult immunization among specific NCIRD priority populations. The four priority groups identified are racial and ethnic minority populations, pregnant persons, rural communities, and adults with chronic medical conditions. This signals that the CDC is looking for projects that do more than measure overall vaccination improvements; it is also looking for approaches that can address equity-related gaps and practical access barriers that affect adults who are historically underserved, at higher risk of complications, or less likely to receive recommended vaccines. Applicants would be expected to keep these populations in view when designing interventions, selecting settings and partners, choosing outcomes to evaluate, and interpreting results.

In terms of funding structure, the award ceiling is listed as $500,000, and the NOFO anticipated making one award. With only a single expected award, the competition is structured to support one primary project (or one coordinated effort) rather than multiple smaller projects. The fact that the instrument is a cooperative agreement also suggests that the selected awardee would likely coordinate closely with CDC subject matter experts, align evaluation methods with CDC priorities, and share findings in ways that can be translated into guidance or practical tools for immunization programs and provider organizations.

Eligibility is broad and includes multiple levels of government and a wide range of organizational types. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; other Native American tribal organizations; and nonprofit organizations both with and without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories). The NOFO also includes an "Others" category with a note to consult the additional eligibility text for clarification, indicating that additional entities may qualify depending on the specific guidance in the full announcement.

The timeline information provided indicates the opportunity was created on November 4, 2022, with an original application closing date of January 13, 2023. Applications were required to be submitted electronically by 11:59 pm Eastern Time on the due date. The listing also notes the CFDA number 93.185, which is the catalog reference used to track the assistance program under which the funding is offered.

Overall, this funding opportunity is best understood as a targeted research-and-evaluation effort focused on improving how adult vaccines are delivered in healthcare settings, and on generating evidence about which quality improvement methods are effective, feasible, and scalable. It seeks to connect provider-level change strategies with the broader enabling role of immunization programs and health departments, while centering outcomes for adult populations where vaccination gaps and preventable disease risks remain especially significant.

  • The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Understanding Adult Immunization Quality Improvement Approaches Among Adult HCP and Health Departments" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.185.
  • This funding opportunity was created on Nov 04, 2022.
  • Applicants must submit their applications by Jan 13, 2023 Electronically submitted applications must be submitted no later than 1159 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $500,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Others (see text field entitled Additional Information on Eligibility for clarification).
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